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Design

Kontex Hybrid Granulation Production Line for Food and Pharmaceutical Industry – Product Description

I. Overview

The Kontex hybrid granulation production line for the food and pharmaceutical industry is centered around the KH series high-intensity mixer. It integrates mixing, granulation, drying, and sizing into a single process, enabling complete production from powder to finished granules in a sealed, clean environment. The line fully complies with GMP and food safety standards.

II. Core Equipment: KH Series Mixer Granulator

Working Principle: Materials are driven by the agitator to form a three-dimensional compound motion. The binder, introduced via atomized spray, forms liquid bridges that aggregate into granules. These are then shaped into uniform particles by the chopper.

Key Parameters:

ParameterSpecification
Processing Capacity1L – 2000L+
Energy Consumption35%-55% lower than conventional equipment
MaterialStainless steel, compliant with GMP standards

Integrated Functions: Dry mixing, wet granulation, drying, cooling – reducing material transfer loss and contamination risks.

III. Production Line Configuration

Laboratory Series:

  • KH01 (1L): Advanced R&D

  • KH02 (2-5L): R&D and small-scale trials

  • KH05 (10-50L): Pilot scale-up

  • KH100 (1-100L variable): Full coverage from R&D to pilot scale

Production Scale Line:

  • Upstream: Vacuum feeding system, pressurized binder addition system

  • Core: KH series granulator main unit, wet sizing system

  • Downstream: Fluid bed dryer, automatic lift mixer, transfer hopper

  • Auxiliary: Universal pulverizer

IV. Industry Features

GMP Compliance: Stainless steel construction, mirror-polished surfaces, dead-corner-free design. Optional CIP (Clean-in-Place) system available. Closed operation prevents cross-contamination.

Special Material Handling:

  • Heat-sensitive ingredients: Low-temperature granulation process

  • Highly active APIs (HPAPI): Closed system prevents exposure

  • Taste masking: Optimized particle morphology to mask undesirable tastes

Intelligent Control: PLC/HMI system enables precise adjustment of speed, temperature, spray rate, etc. Supports multi-stage process programming, data traceability, and recipe management.

V. Product Advantages

Advantage CategorySpecific Benefits
Process IntegrationIntegrates dry mixing, wet mixing, granulation, and drying. Reduces binder usage by 25%, improves efficiency by 4-5 times.
Product QualitySpherical granules with good flowability, narrow particle size distribution, and uniform content.
Operating CostsEnergy consumption reduced by 35-55%; small footprint; lower investment.
Service SupportPre-sales validation testing, on-site installation and training during sales, post-sales technical support.

VI. Conclusion

The Kontex hybrid granulation production line provides food and pharmaceutical companies with a complete solution from laboratory R&D to full-scale production. Based on the design concepts of integration, automation, and traceability, it supports the continuous upgrading of granulation processes.


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CONTACT US

Contact: Kevin zhang

Phone: +86 15720553151

E-mail: azws@kontex-metco.com

Whatsapp:+86 15720553151

Add: No. 35, Gutan Avenue, Gaochun District, Nanjing